PhD courses
Speciality Code:
8D05105
Speciality Name:
Biotechnology
Faculty:
Biology and Biotechnology
Qualification:
- Scientific and pedagogical direction - Doctor of Philosophy (PhD)
- Model of graduating student
- Mandatory disciplines
- Elective disciplines
- Professional
LO1: generate original ideas for the creation of new technologies and innovative products for biomedicine, bioinformatics, agriculture, ecology, food industry, etc.
LO2: develop, plan and conduct original scientific research based on modern theories and methods of analysis in the field of biotechnology;
LO3: apply modern information technologies and specialized programs for processing the received data;
LO4: critically evaluate the results and draw adequate conclusions based on the obtained experimental data.
LO5: present the results of the work performed in the form of reports, reviews, presentations, scientific reports and publications in rating publications;
LO6: carry out teaching activities on educational programs of higher education in the field of biological sciences, using innovative methods in the educational process;
LO7: apply a set of acquired knowledge and skills in organizational activities, management of a scientific or production team, developing strategic and operational plans for the development of government organizations, firms, enterprises, companies, etc.
LO8: develop and implement quality management systems for biotechnological products.
LO2: develop, plan and conduct original scientific research based on modern theories and methods of analysis in the field of biotechnology;
LO3: apply modern information technologies and specialized programs for processing the received data;
LO4: critically evaluate the results and draw adequate conclusions based on the obtained experimental data.
LO5: present the results of the work performed in the form of reports, reviews, presentations, scientific reports and publications in rating publications;
LO6: carry out teaching activities on educational programs of higher education in the field of biological sciences, using innovative methods in the educational process;
LO7: apply a set of acquired knowledge and skills in organizational activities, management of a scientific or production team, developing strategic and operational plans for the development of government organizations, firms, enterprises, companies, etc.
LO8: develop and implement quality management systems for biotechnological products.
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PhD thesis writing and defence
- Number of credits: 12
- Type of control: Докторская диссертация
- Description: The main purpose of "PhD thesis writing and defence": of a doctoral dissertation is the formation of the doctoral students' ability to disclose the content of research work for the defense of the thesis. During the study of course, doctoral student's should be competent in: 1. to substantiate the content of new scientifically grounded theoretical and experimental results that allow to solve a theoretical or applied problem or are a major achievement in the development of specific scientific directions; 2. explain the assessment of the completeness of the solutions to the tasks assigned, according to the specifics of the professional sphere of activity; 3. they can analyze alternative solutions for solving research and practical problems and assess the prospects for implementing these options; 4. apply the skills of writing scientific texts and presenting them in the form of scientific publications and presentations. 5. to plan and structure the scientific search, clearly highlight the research problem, develop a plan / program and methods for its study, formalize, in accordance with the requirements of the State Educational Establishment, the scientific and qualification work in the form of a thesis for a scientific degree Doctor of Doctor of Philosophy (PhD) on specialty «8D07502 – Standardization and certification (by industry)». During the study of the discipline doctoral student will learn following aspects: Registration of documents for presentation of the thesis for defense. Information card of the dissertation and registration-registration card (in the format Visio 2003). Extract from the minutes of the meeting of the institution, in which the preliminary defense of the thesis took place. Cover letter to the Higher Attestation Commission. Expert conclusion on the possibility of publishing the author's abstract. Expert opinion on the possibility of publishing a dissertation. Minutes of the meeting of the counting commission. Bulletin for voting. A shorthand record of the meeting of the dissertational council. List of scientific papers. Response of the official opponent. A review of the leading organization. The recall of the scientific adviser.
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Academic writing
- Number of credits: 2
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to develop practical skills of writing academic texts for doctoral students in order to present the results of their work in the form of reports, reviews, scientific reports and publications in rating publications indexed in Scopus that meet the criteria of non-predatory publications. Within the discipline, doctoral students improve their skills in analyzing and presenting of scientific information in various forms.
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Methods of Molecular Biotechnology
- Number of credits: 5
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability to apply modern molecular methods of biochemistry, biophysics, molecular biology and genetics, which are widely used in biotechnology. Upon completion of the study of this discipline, doctoral students will be able to: 1. demonstrate a systematic understanding of experimental approaches to the study of biotechnology objects at the molecular level; 2. plan and develop a scientific study using molecular methods; 3. conduct an experiment to study the structural and functional organization of bioobjects using molecular methods; 4. critically evaluate and analyze the experimental results obtained; 5. present the results of the work performed in the form of scientific and technical reports, reviews, presentations. The discipline includes: experimental approaches to the study of biotechnology objects at the molecular level; advances in the application of molecular methods in the study of biological objects; advances in the study of the structural and functional organization of bioobjects by molecular methods.
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Scientific Research methods
- Number of credits: 3
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: Purpose: to form the ability to apply modern methods and methodologies of scientific research when performing a doctoral dissertation. Here are considered: methods and methodologies of scientific research; modern experimental approaches to the scientific research of a doctoral student; stages and principles of planning a scientific experiment.
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Development and Production of Biotechnological Products
- Number of credits: 5
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability to develop modern technologies for the production of biotechnological products for: healthcare, agriculture, environmental protection, food and processing industries. Upon completion of the study of this discipline, doctoral students will be able to: 1. evaluate and predict current trends in the use of biological objects that are raw materials for biotechnological production; 2. demonstrate knowledge of modern methods used to produce new biotechnological products: microbial processes, genetic engineering, etc. 3. analyze and critically evaluate the main directions and prospects for the development of modern biotechnological production, biotechnological facilities; 4. plan, develop and implement the experimental design with the aim of obtaining new biotechnological products; 5. develop methodological approaches and solutions to the production problems of modern industrial biotechnology; Within the framework of this discipline the following topics are considered: current trends in the development of modern biotechnology; features of biotechnological production; characteristics and biotechnological potential of biological objects; New technologies in obtaining products for industry, medicine and agriculture. Critical moments of individual stages of biotechnological production. New technologies based on immobilized enzymes and microbial cells. Examples of biotechnological processes for obtaining products of practical value. Prospects of production using immobilized enzymes and microbial cells. Technologies of production of biologically active substances. Problems in carrying out individual stages of bioprocesses.
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Bioinformatics in systems biotechnology
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The aim of the course - to familiarize students with complex interactions in living systems using computer and information technology. During the study of course, students should be competent in: 1. applying computer and information technology to study systems biology and biotechnology; 2. use such techniques as transcriptomics, metabolomics, proteomics and other high-performance technologies to collect numerical data; 3. demonstration skills in the development of computer models of complex biological systems; 4. develop with the help of computer technology a practical system level framework for solving problems in various fields of biomedicine; 5. prediction the use of models constructed on the basis of quantitative data on the elementary processes that make up the system in biotechnology. Course content: application of modern methods of computer and information technology to study the interactions between the constituent parts of biological systems and the study of the mechanisms of formation of functions and system properties as a result of these interactions.
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Bioinformatics in socially significant diseases
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to familiarize students with the IT-technologies of searching for potential drugs and targets for the treatment of socially significant diseases. Upon completion of the study of this discipline doctoral students will be able to: 1. evaluate and predict current trends, trends and patterns in the development of bioinformatics; 2. to process and further analyze a large body of information on biological objects (decrypted genomes, spatial structures of biomolecules, interaction of biological objects); 3. to develop methods of molecular diagnostics and selection of new targets for drugs based on informational studies of genomes; 4. use bioinformatics methods in molecular diagnostics of socially significant diseases; 5. apply modern information technologies and specialized programs for processing the obtained data and their bioinformatics analysis; Within the discipline are considered: the use of databases of relevant substances, the combination of their structures using computer technologies for the introduction of candidates for drugs, the study of chemo informatics, the use of a virtual screening database of libraries.
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Bionanotechnology
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability to use knowledge and skills in the field of bionantechnology for medicine, food industry, etc. As a result of studying the discipline, doctoral students will be able to: 1. demonstrate systemic knowledge of biological nanostructures with different properties, bionan elements; 2. argue the possibility of using the principles of the functioning of bioanostructures (macromolecules, genes, cells) in modern nanobiotechnologies; 3. evaluate the achievements and prospects for the development of nanobiotechnology; 4. analyze the biochemical, biophysical and molecular biological basis of bionanotechnology; 5. generate projects that stimulate both the fundamental development of bionanotechnology and its commercialization aimed at improving the quality of life and health of people Specific topics include:The variety of biological nanostructures and their properties.Unique properties of the bionon elements that are used in technological devices and processes.Creation and application of various devices using bionanobjects.The connection of fundamental science with production on the basis of high bionanotechnologies.Modern directions of development of nanobiotechnology.Principles and organization of work of bionanomachines.The use of DNA molecules in nanobiotechnology.Principles of bionanotransport. Biosensors and their use. Modern lines of research in the field of biosensorics. Nanomedicine. Bionanomaterials. Prospects for the development of nano-biotechnology.
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Bioenrgy of Phototrophic Microorganisms
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability to use the methods of microbiological production of renewable energy sources using phototrophic microorganisms. Upon completion of the study of this discipline, doctoral students will be able to: 1. demonstrate systemic knowledge of the physiological and biochemical characteristics of phototrophic microorganisms used to produce biofuels; 2. describe the features of the metabolism of phototrophic microorganisms - sources of biofuel production; 3. develop ways to increase the productivity of phototrphic microorganisms; 4. formulate the prospects of using phototrophic microorganisms in biotechnological processes to solve environmental, energy and raw materials problems. 5. synthesize new ideas for the use of phototrophic microorganisms in biotechnological processes to solve environmental, energy and raw materials problems. When studying the discipline, doctoral students should acquire knowledge of a holistic approach to the study of photosynthesizing cells and organisms, the possibility of using photosynthetic microorganisms for the needs of biotechnological production; cultivation technologies of microalgae - oil producers for the production of biodiesel fuel.
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Genomics and Gene Diagnostics
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability to demonstrate a systematic understanding of the main tasks of genodiagnostics and genomics. By the end of the module, students will be able to: 1. demonstrate a systematic understanding of the main tasks of genodiagnostics and gene therapy; 2. critically evaluate the practical and theoretical foundations of methods for analyzing genomes; 3. plan and conduct integral genodiagnostic and general laboratory research; 4. correctly operate the instruments and materials necessary for carrying out genome research. 5. predict and analyze the results of a molecular genetic experiment Within the framework of this discipline, the latest achievements of molecular genetics in the field of genomics and gene diagnostics are considered, which provide, among other things, understanding of the biochemical, physiological, molecular and other key processes occurring in a human body. The discipline provides knowledge of mutation detection methods, molecular diagnostic features, state and prospects of gene therapy of various hereditary diseases.
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Dispersive Analysis in Biotechnology
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: Upon completion of the study of this discipline doctoral students will be able to: 1. plan and implement a variance analysis of qualitative traits; 2. demonstrate skills in collecting and processing experimental data required in engineering practice and research activities; 3. demonstrate the skills of mathematical modeling of production problems, search for their optimal solution, analysis and evaluation of the results obtained; 4. apply the basic techniques of mathematical modeling in solving problems of different nature; 5. demonstrate the skills of conducting the difference method, analysis of variance of single-factor and multifactor experiment, correlation and regression analyzes; Within the discipline are considered: the statistical impact of one or several factors on the resultant feature; various types and modifications of analysis of variance, methods for assessing the strength of influence and reliability of influences of factors; estimation of the difference between private averages and private shares; forecasting the development of the trait under a given set of conditions.
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Commercial biotechnology
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability of doctoral students to use knowledge in the field of commercial biotechnology. Upon completion of the study of this discipline doctoral students will be able to: 1. demonstrate systemic knowledge and understanding of the current state, methods and directions of development of commercial biotechnology on a national and transnational scale; 2. systematize modern approaches for creating, developing and analyzing the activities of commercial biotechnology companies, including in the context of the student environment; 3. choose the strategy and tactics of conducting commercial transactions with products of biotechnology to overcome risk factors and inept administrative actions, as well as other factors affecting the productivity of biotechnological processes. 4. apply the most effective alternative methods of commercial biotechnology; 5. forecast further breakthroughs in commercial biotechnology. The following topics are covered within the framework of this discipline: the study of commercially attractive biotechnological products, the conditions for their production, marketing, marketing, and the derivation of a derivative of innovative products; overview of major transnational and national commercial biotech industries; the main rules in the process of establishing and developing a commercial biotechnology company; profitable biotech business as an integral and advanced part of biotechnology.
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Metabolic engeneering
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability to apply modern methods of metabolic engineering, which are used to study the metabolism of various organisms and its directed modification. Upon completion of the study of this discipline doctoral students will be able to: demonstrate a systematic understanding of the scientific problems in the field of metabolic engineering; evaluate the research methodology in metabolic engineering;justify the strategy of creating a new generation of microorganisms-producers of primary and secondary metabolites; to predict the results of fundamental molecular biology, genetics and biochemistry for the creation of new producers with the metabolically regulated expression of biosynthetic genes.
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Bioinformatics in bioengineering
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The aim of the course is to form the ability to use bioinformatics technologies in animal, plant and microorganism bioengineering. During the study of course, students should be able to: 1. apply modern approaches characteristic of bioengineering and bioinformatics to solve problems facing both fundamental and applied science; 2. use the acquired knowledge and professional skills for competent analysis of a large amount of information and scientific data on biological objects (decrypted genomes, spatial structures of biomolecules, interaction of biological objects); 3. understand the basic principles of modified or new biological objects designing 4. use methods of bioinformatics and bioengineering in molecular diagnostics, selection of new targets for drugs, medical and genetic research; 5. master the methods of observation, description, identification and scientific classification of biological objects; Course content: The use of information and computer technology in the genetic engineering of organisms. Molecular basis of cell culture. The study of structural and functional features of the mitochondrial and chloroplast genomes. Development of methods for molecular diagnostics and selection of new targets for drugs. The study of bioinformatics approaches to solving problems of biotechnology, acquaintance with new methods of preserving natural resources, plant and animal life.
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Nutrient Potential of Food Raw Materials
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline - to form the ability to demonstrate a holistic knowledge of the system of food raw materials and its potential. At the end of the course the doctoral students will have the following abilities: 1. demonstrate systemic knowledge of the processes of biotechnological transformation of the properties of food raw materials; 2. explain the processes occurring in food raw materials during storage and processing; 3. analyze the processes that occur with food substances when ingested; 4. evaluate the principles, methods and approaches of quantitative and qualitative analysis of structure formation in food systems; 5. predict chemical, physical-chemical, colloidal, biochemical transformations in food raw materials; The discipline considers: sources and methods of processing food raw materials using biotechnological methods. Food raw materials as a multicomponent, multifunctional, biologically active system. Biotechnological and biogenic potential of food raw materials. Functional and technological properties of raw materials, food additives and food systems.
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Bioavailability, Biotransformationof Xenobiotics and Natural Polymers
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability of undergraduates to analyze the theoretical foundations of the toxic effects of xenobiotics and their metabolic pathways in a living organism. The course includes the study of the interaction of xenobiotics or products of its biotransformation in the body with the structural elements of Biosystems. As well as within the discipline the General characteristics of separate groups of xenobiotics, their main phases of biotransformation and biochemical mechanisms of xenobiotics biodegradation are considered.
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Molecular Biology of Microorganozms
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability to demonstrate systemic knowledge about the molecular characteristics of microbial systems and the processes they carry out. As a result of studying the discipline, the doctoral student will be able to: 1. demonstrate a systematic understanding of the molecular features of microbial systems; 2. explain the molecular processes occurring in microbial systems; 3. select and develop technologies for the production of microbial synthesis; 4. evaluate the prospects for the use of microbial systems in molecular biotechnology; 5. analyze the prospects for the use of microbial systems in molecular biotechnology; Specific topics includes: structural and functional organization of micro-organisms, the practical use of microorganisms in biotechnological processes to obtain products through microbial systems, the molecular basis of microbial synthesis, the prospects for the use of microbial systems in molecular biotechnology; metagenomic analysis of microbial communities.
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Molecular biotechnology of pro- and eukaryots
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability to demonstrate systemic knowledge in the field of molecular biotechnology of pro and eukaryotic organisms. As a result of studying the discipline, the doctoral student will be able to: 1. demonstrate systemic understanding in the field of molecular organization of pro and eukaryotic; 2. analyze and use theoretical knowledge about the structure of pro- and eukaryotic genomes to solve problems of biotechnology; 3. select the conditions necessary for effective expression of proteins in the desired host organism; 4. assess the possibility of using recombinant microorganisms for industrial protein synthesis; 5. predict the results of experimental studies on the expression of foreign genes in plants; Within the framework of the discipline, technological methods for changing the properties of industrial strains based on the methods of mutagenesis, gene and cell engineering are considered; basic technologies used in molecular, cellular bio- and nanotechnologies; modern analytical and molecular research methods in molecular biotechnology. The use of pro- and eukaryotes for the expression of foreign proteins. The use of recombinant microorganisms to obtain commercial products.
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Proteomical Technologies
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The aim of the course is to study the prospects of using modern proteomic technologies in medicine, pharmacology, and industrial production. As a result of studying the discipline, doctoral students will be able to: 1. demonstrate a systematic understanding of modern methods of studying proteomes; 2. argue the possibilities of using proteomic technologies for diagnostic purposes; 3. apply bioinformatic technologies for processing the results of proteomic experiments on the modeling of structure, dynamics, protein function and complex nanomolecular systems. 4. substantiate the possibilities of using proteomic technologies for control over the quality of food products; 5. predict and search for biomarkers for diagnostics, prognosis of the course or monitoring of therapy of socially significant diseases with the help of proteomic technologies; Course content: Proteomics: new technologies in biology and medicine. Use of proteomic technologies for creation of methods for diagnosis of various diseases, to search for diagnostic markers of disease. Different approaches in the use of proteomic technologies to identify biomarkers. Stages of proteomic analysis. Technology development of proteomic analysis in the formation of instrumentation for molecular diagnostics. Using proteomics technology to create quality control methods of various food products. Proteomic technologies in the field of personalized medicine for the development of medical diagnostic equipment, the creation of new medicines, diagnosis and treatment of socially significant and rare diseases.
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Modern Methods of Research of Genetically Modified Raw Materials
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline - to form the ability to use the methods of detection and analysis of genetically modified organisms and products derived from them. As a result of studying the discipline, the doctoral student should be able to: 1. demonstrate systemic knowledge about methods of DNA extraction from different biological material; 2. explain the features of the GMF and their possible impact on the human body; 3. apply the methods of standard tests to determine the composition, functional-technological and physico-chemical properties of food raw materials, materials and finished products; 4. plan and conduct research to obtain GMF; 5. develop legislative acts regulating the production and trade of GM food products. Contents: Methods for DNA extraction. PCR analysis in the identification of GM products. Determination of GMOs using standardized test chip systems. The principle of the hybridization of complementary DNA labeled deposited on the chip. Methods based on quantitative determination of nucleic acids. Methods for obtaining the GMO: Agrobacterium-mediated transfer, ballistic transformation, electroporation and viral transformation. The legislation, which regulates the admission, trade and labeling of GM foods.
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Modern Problems of Photobiotechnology
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is to form the ability to use knowledge of the biology of phototrophic microorganisms to solve biotechnological problems. Upon completion of the study of this discipline, doctoral students will be able to: 1. demonstrate systemic knowledge of the cultural-morphological, physiological-biochemical properties of phototrophic microorganisms; 2. describe modern methods of mass cultivation of phototrophic microorganisms for obtaining biomass; 3. compare the features of photosynthesis of different groups of phototrophs, their properties and classification, the role in nature and human life; 4. Use microalgae in mass cultivation to produce biologically active substances; 5. To justify the significance of the results of the project study in its own professional development and in the development of the scientific paradigm of biotechnology. Course topics: The importance of advances in the biotechnology of phototrophic microorganisms, the main properties of phototrophic microorganisms, their classification, the role in nature and human life, the possibility of using microalgae for their mass cultivation. Biotechnology of food additives and biologically active substances on the basis of cyanobacteria and microalgae. Producing a protein based on microalgae. Preparation of fodder additives based on cyanobacteria and microalgae. The role of cyanobacteria in the development of photobiotechnology. Phototrophic microorganisms as objects in biomonitoring of aquatic ecosystems. Biodegradation of oil contamination components involving cyanobacteria. Biofuel based on phototrophic microorganisms. Photobioreactors for biomass production of phototrophic microorganisms.
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Theoretical Basis of Nutritional Biochemistry
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline - to form the ability to demonstrate knowledge in the field of nutrition biochemistry, aimed at the organization of balanced nutrition and healthy lifestyles. Upon completion of the study of this discipline, doctoral students will be able to: 1. demonstrate systemic knowledge about the functions of nutritional substances and their role for the human body; 2. evaluate the principles of rational human nutrition for the preservation of his health; 3. plan and implement modern methods of researching the composition and quality of food. 4. сritically analyze the consequences of nutrient intake in excess or inadequate quantities 5. substantiate the basic principles of rational nutrition. The discipline includes: modern scientific theories of nutrition; principles of nutrition; calorie diet; nutritional value of food. Features of the metabolism of individual substances. Principles of rationing. Nutrition culture of a healthy person.
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Phythopathology and technologies of plants defence
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: Upon completion of the study of this discipline, doctoral students will be able to: 1. demonstrate systemic knowledge about the biological features of the main types of pests and pathogens of plant diseases; 2. classify environmental factors that cause non-infectious diseases and affect the change in the number of pests and disease dynamics; 3. plan and develop methods and technologies for protecting vegetable, berry, fruit, medicinal, essential oil, ornamental and horticultural crops; 4. Assess the phytosanitary status of crops and plantations, plan their protection systems against pests; 5. offer modern methods of diagnostics of pests and pathogens of plant diseases; Within the discipline are considered: the classification of plant diseases; causative agents of plant diseases (viruses, viroids, bacteria), their characteristics; modern methods of plant protection against pathogens; biological plant protection against phytopathogens; technologies for producing polyfunctional drugs of various spectra of action.
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Pedagogical
- Type of control: Защита практики
- Description: Aim оf discipline: formation of the ability to carry out educational activities in universities, to design the educational process and conduct certain types of training sessions using innovative educational technologies.
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Research
- Type of control: Защита практики
- Description: The purpose of the practice: gaining experience in the study of an actual scientific problem, expand the professional knowledge gained in the learning process, and developing practical skills for conducting independent scientific work. The practice is aimed at developing the skills of research, analysis and application of economic knowledge.