Magistracy
Speciality Code:
7M05119
Speciality Name:
Reproductive genetics
Faculty:
Biology and Biotechnology
Qualification:
- Scientific and pedagogical direction - Master of Natural Sciences
- Model of graduating student
- Mandatory disciplines
- Elective disciplines
- Professional
LO1. Analyze the genetic patterns of human embryonic and ontogenetic development at the molecular, cellular, organismal levels;
LO 2. Interpret the causes and mechanisms of molecular genetic and epigenetic variability;
LO 3. Use molecular genetic methods to diagnose developmental disorders of the embryo and fetus;
LO 4. Determine the genetic factors of female and male infertility using molecular genetic methods;
LO 5. Apply methods of assisted reproductive technologies (preimplantation genetic testing, in vitro fertilization, prenatal diagnosis of hereditary pathology, etc.) to solve the problem of infertility;
LO 6. Develop actionable recommendations based on representative and original analysis results;
LO 7. Analyze scientific, technical and patent information on research topics using information technology;
LO 8. Develop and introduce theoretical and applied disciplines into the educational process based on a student-centered approach using digital technologies, interactive methods, forms and teaching aids;
LO 9. Design and implement comprehensive research, including interdisciplinary, based on the analysis of fundamental and applied problems in the field of reproductive genetics;
LO 10. Plan professional activities taking into account ethical and legal norms and principles of bioethics;
LO 11. Develop a plan for research work and present the results of independent research to the scientific community;
LO 12. Improve professional and personal self-education and be able to work in a team.
LO 2. Interpret the causes and mechanisms of molecular genetic and epigenetic variability;
LO 3. Use molecular genetic methods to diagnose developmental disorders of the embryo and fetus;
LO 4. Determine the genetic factors of female and male infertility using molecular genetic methods;
LO 5. Apply methods of assisted reproductive technologies (preimplantation genetic testing, in vitro fertilization, prenatal diagnosis of hereditary pathology, etc.) to solve the problem of infertility;
LO 6. Develop actionable recommendations based on representative and original analysis results;
LO 7. Analyze scientific, technical and patent information on research topics using information technology;
LO 8. Develop and introduce theoretical and applied disciplines into the educational process based on a student-centered approach using digital technologies, interactive methods, forms and teaching aids;
LO 9. Design and implement comprehensive research, including interdisciplinary, based on the analysis of fundamental and applied problems in the field of reproductive genetics;
LO 10. Plan professional activities taking into account ethical and legal norms and principles of bioethics;
LO 11. Develop a plan for research work and present the results of independent research to the scientific community;
LO 12. Improve professional and personal self-education and be able to work in a team.
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Genetics of infertility and assisted reproductive technologies
- Number of credits: 9
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to analyze the genetic causes of the formation of female and male infertility. The following aspects will be considered: molecular-genetic methods for diagnosing infertility; mutations in the CFTR, AZF, AR, SRY genes; numerical and structural chromosomal abnormalities in infertility; assisted reproductive technologies (intrauterine insemination, ICSI, IVF, assisted hatching, cryopreservation, etc.).
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Genomics and Molecular Diagnostics
- Number of credits: 6
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to analyze the content, organization, implementation of genomic information and apply methods of molecular diagnostics of genetic diseases. The following aspects will be considered: structure, organization, levels of functioning, stability and polymorphism of genomes in professional activities; methods of molecular diagnostics (DNA extraction, PCR analysis, DNA electrophoresis); analysis the results obtained using bioinformatic technologies.
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Foreign Language (professional)
- Number of credits: 6
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose is to acquire and improve competencies by international standards of foreign language education and to communicate in an intercultural, professional, and scientific environment. A master's student must integrate new information, understand the organization of languages, interact in society, and defend his point of view.
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History and Philosophy of Science
- Number of credits: 3
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: Purpose: Understanding of modern philosophy as a system of scientific knowledge, including worldview in rational-theoretical comprehension. The discipline includes aspects of the evolution and development of scientific thinking, historical moments, the contribution of scientists and scientific schools to the formation of science, and ethical and social aspects of scientific activity.
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Cell and Genetic engineering
- Number of credits: 6
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to analyze the achievements of cellular and genetic engineering for editing the genome of the embryo. The following aspects will be considered: ways to create diagnostic products for detection of genetic abnormalities of the embryo, the using of CRISPR / Cas9 technology for the treatment of hereditary diseases and infertility; methods of culturing embryos, stem cells.
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Organization and planning of scientific research
- Number of credits: 6
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline is: to form the ability to use theoretical and practical knowledge to set and solve research problems and to control the teaching and research activities of students in the field of biological education. The following issues are considered: educational and research activities.
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Pedagogy of Higher Education
- Number of credits: 3
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: Purpose: To provide pedagogical theories and practical strategies for effective teaching in higher education, fostering critical thinking, and academic success. The course explores instructional methods, curriculum design, assessment techniques, and classroom management strategies preparing educators to create inclusive and stimulating learning environments.
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Psychology of management
- Number of credits: 3
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: Formation of knowledge about the fundamental concepts of management psychology for the practical application of the most critical aspects of management in professional interaction. The following will be studied: basic principles of management psychology, personality in management interactions, management of personality behavior, modern ideas, psychology of managing group phenomena, motivation, and practical reflection.
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Reproductive biology and developmental genetics
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to analyze the mechanisms of reproduction and the genetic patterns of the development of the organism. The following aspects will be considered: the formation and development of the human reproductive system, the mechanisms of fertilization and gametogenesis; the genetic mechanisms of embryo development; genetic approaches and methods for studying embryogenetic and ontogenetic mechanisms of development; the general patterns of genetic regulation of individual development.
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Human genome and proteomics
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to analyze the data obtained as a result of sequencing of the human genome for specific research tasks. The following aspects will be considered: master the methods of obtaining biological information (sequencing, micro-chips, mass spectrometry), use biological information databases (GenBank, UniProt, Ensembl, etc.); use methods of analysis of genomic, metagenomic, transcriptomic, proteomic data; computer visualization tools for the analysis of nucleotide sequences.
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Immunogenetics and pharmacogenetics
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to analyze the molecular-genetic basis of immunity and the individual variability of the effects of drugs. The following aspects will be considered: molecular-genetic methods to determine the hereditary factors of immunity, depending on the individual response of the body to drugs; the possibility of individualizing the choice of drugs and their dosing regimens based on the study of the genotype of a particular patient.
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Information technologies in genetics
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to use computer programs for the statistical analysis of the database of clinical and laboratory data. The following aspects will be considered: methodological techniques of statistics in genetics and biomedicine; statistical data analysis using software (Statistica, SPSS, STATA) and programming languages (R, Python); determination the statistical significance of differences in the compared data and interpretation the results.
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Molecular cytogenetics
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to analyze chromosomal abnormalities using molecular cytogenetic methods of research. The following aspects will be considered: the structural and functional features of human chromosomes; the mechanisms of interaction of the molecular components of the chromosome; the mechanisms of formation of systemic mutations as a result of chromosome reorganization; molecular cytogenetic methods (FISH, SKY, PCR and microarray analysis of chromosomes) for the diagnosis of hereditary diseases and infertility.
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Mutagenesis and epigenetics
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to analyze the patterns of mutagenesis and epigenetic inheritance. The following aspects will be considered: the theoretical and experimental foundations of the mutation process; the cause of hereditary pathologies; patterns of epigenetic inheritance and epigenetic mechanisms of embryonic stem cell differentiation; the mechanisms and ways of realization of epigenetic signals in the cell; epigenetic aspects of infertility.
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Reproductive endocrinology and psychology
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to analyze the influence of sex hormones and psychological aspects in the implementation of the reproductive function, including problems of reproductive health. The following aspects will be considered: the causes and mechanisms of typical disorders of sexual development and diseases of the genital organs; the possible psychological causes of reproductive health disorders; interpretation the results of hormonal testing in the diagnosis of endocrine reproductive disorders.
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Clinical genetics and bioethics
- Type of control: [RK1+MT+RK2+Exam] (100)
- Description: The purpose of the discipline: to form the ability to analyze the patterns of manifestation of hereditary pathologies and genetic causes of infertility. The following aspects will be considered: the molecular, biochemical, cytological bases of genetic diseases; making a pedigree to determine the type of inheritance of the disease; the contribution of the hereditary factor to the population frequency of manifestation of pathology; methods of prevention, diagnosis and treatment of hereditary diseases; principles of bioethics in clinical genetics.
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Pedagogical
- Type of control: Защита практики
- Description: Aim оf discipline: formation of the ability to carry out educational activities in universities, to design the educational process and conduct certain types of training sessions using innovative educational technologies.
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Research
- Type of control: Защита практики
- Description: The purpose of the research practice is acquaintance with the latest theoretical, methodological and technological achievements of domestic and foreign science, with modern methods of scientific research, processing and interpretation of experimental data. During the study of course, students should be competent in: - to understand the fundamental and applied research; - to understand the level of research, the stage of scientifically-research work - planning, organization and realization; - preparation, writing, representation and review of the project; - program research, methodological and procedural sections research; - systematize the base of scientific and technical information.